The 2021 World Hospital Congress taking place in November will provide us an enhanced opportunity to exchange knowledge and best practices on healthcare transformations driven by people, value and technology. Considering how COVID-19 has challenged healthcare organizations, it is critical to discuss how these transformations contribute to the enhancement of responsiveness, flexibility and resilience. We are opening the 2nd Call for Abstracts this March for projects and programs that demonstrate transformations key to achieving agility, guaranteeing adequate responsiveness and improving the resilience of healthcare systems and hospitals. Stay tuned!